Sentence examples for model harbors a from inspiring English sources

The sod1 zebrafish ALS model harbors a fluorescent heat shock stress response (HSR) reporter gene (hsp70-DsRed).

Our mouse model harbors a truncation variant in A-band TTN, making it a good mouse model for a wide spectrum of human DCM.

The myodystrophy Large myd mouse model harbors a mutation in the gene Large, which encodes a glycosyltransferase that presumably alters the glycosylation of α-DG.

This autochthonous model harbors a KrasG12D mutation and overexpresses Twist1 and Ddx3, which made it a suitable model to test efficacy of RK-33 (Fig 6B).

To validate our findings in vivo, we initially used an orthotopic xenogeneic mouse model and, subsequently, an orthotopic syngeneic mouse model, since the latter model harbors a functional immune system.

This model harbors an Abcc6 missense mutation, causing truncation of the protein via the presence of an additional donor splice site.

To directly assess the levels of different types of spontaneous mutations in organs and tissues during aging, we have used a mouse model harboring a chromosomally integrated cluster of lacZ-containing plasmids that can be recovered and analyzed in Escherichia coli.

We next took advantage of a previously published rat model harboring a disease-causing point mutation in the gene encoding MKS3 [18], which results in polycystic kidney disease [17] as well as hydrocephalus [9].

While the Apc-Cdkn1a network was generated using tumor-specific ApcMin/+ data – a model harboring a number of background genetic lesions [41] – the intestinal tissue obtained from the Apc1638N+/− and Cdkn1a−/− mice at 3 months of age is relatively polyp free, thus allowing us to gauge the effect of a single genetic perturbation on the pre-neoplastic epithelium.

Moreover, young mouse model harboring a mutation favoring generation of Aβ 1-42 over Aβ 1-40 had a low Aβ 40/42 ratio, was shifted to plaque deposition [ 45].

Other studies have examined the expression of the C9orf72 gene using a transgenic mouse model harboring a targeted LacZ insertion [ 32].