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120 healthy Sprague-Dawley rats were randomly divided into 5 groups, Sham-operated group (group S), model group (group M), group K, group C and group CP.
The rats were randomly divided into a control group (group A), model group (group B) and sFRP1 group (group C), each consisting of 24 rats.
Each of which contained 24 rats, Sham-operated group(group S), model group(group M), Ketotifen treated group(group K), cromolyn sodium treated group(group C) and compound 48/80 treated group(group CP).
Male SD rats were divided into the treatment group (group A) and the model group (group B) consisting of 24 rats each, and were injected intramuscularly with 20 mg/kg methylprednisolone (MP) for 8 weeks, once a week.
Male Sprague Dawley (SD) rats were randomly divided into a control group (group A), model group (group B) and sFRP1 group (group C), each consisting of 24 rats, and the rats were intravenously injected with LPS (10 μg/kg body weight).
Forty-eight animals divided into the treatment group (group A) and the model group (group B) consisting of 24 rats each, all were injected intramuscularly with 20 mg/kg MP (Pfizer Manufacturing, Belgium NV) via bilateral gluteus maximus alternately for 8 weeks, once a week.
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Compared with the model group, groups treated with the metformin and with different proportions of astragaloside and curcumin help lower the blood glucose levels and GSP levels, increase glycogen stores of model mice by different degrees, and avoid pathological changes of pancreas in the model mice.
Compared with the model group, groups treated with ASMq 2 g/kg, 4 g/kg, or 8 g/kg had significantly higher IL-1, IL-2 and TNF-α concentrations.
The regression model included groups (group 1 vs. group 2), movement (neutral, extension, and flexion), load (none, compression, and traction), and side (left vs. right).
The final model included age group, ethnic group and sex, vaccination history, chronic illness, and reported damp housing as independent variables.
A total of 30 mice were randomly assigned to control, model and 1,25(OH)2D3−treated group (each group = 10).
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