Some studies have, however, shown that minimal model analysis from frequently sampled intravenous glucose tolerance tests underestimates insulin sensitivity (59).
Moreover, studies using the minimal model analysis of frequently sampled intravenous glucose tolerance test have revealed lower insulin sensitivity, reduced hepatic insulin extraction and clearance, and increased acute insulin response in AA children and adults compared with EAs (23, 24, 36– 36).
The measurement of in vivo insulin sensitivity was performed using the minimal model analysis of the frequently sampled intravenous glucose tolerance test (FSIVGTT).
Insulin sensitivity was measured at baseline and at 6 months using the frequently sampled intravenous glucose tolerance test with minimal model analysis.
Frequently sampled intravenous glucose tolerance test with minimal model analysis was performed as previously described [ 30].
SI was determined from frequently sampled intravenous glucose tolerance tests with minimal model analysis.
Insulin sensitivity was measured using the frequently sampled intravenous glucose tolerance test with minimal model analysis, as previously described [ 31].
Specifically, nondiabetic African American and Hispanic adults were more insulin resistant than nondiabetic NHW adults, using a frequently sampled intravenous glucose tolerance test with minimal model analysis (8).
In those subjects who agreed (n = 230), insulin sensitivity and glucose effectiveness were measured using the frequently sampled intravenous glucose tolerance test with minimal model analysis.
Furthermore, only the Insulin Resistance Atherosclerosis Study Family Study [ 54] has direct measures of insulin resistance and insulin secretion, in their case based on frequently sampled intravenous glucose tolerance test (FSIGT) with Minimal Model analysis [ 64, 65].
