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The numbers of SNPs with model frequencies and effects that exceeded various thresholds are presented in Table  6 and Table  7.

We show the substitution rates for the 192 off-diagonal elements in our context-dependent model using context-dependent model frequencies and a second-order Markov chain at the ancestral root sequence in Figure 5.

Figure 9 shows (log) Bayes Factors for our context-dependent model with context-dependent model frequencies and Markov chains of different orders at the ancestral root sequence (see also Table S5 in Additional file 1).

We show that the substitution rates associated with the CpG-methylation-deamination process can be modelled through context-dependent model frequencies and that their accuracy depends on the (order of the) Markov chain imposed at the ancestral root sequence.

We have calculated (log) Bayes Factors for our context-dependent model with context-dependent model frequencies and Markov chains of different orders at the ancestral root sequence in the same way as reported above, with the general time-reversible model as the reference model.

As mentioned above, the context-dependent model with context-dependent model frequencies and a second-order Markov chain at the ancestral root sequence yields a a bidirectional mean log Bayes Factor of 7221.47 log units, compared to the independent GTR model (7218.01 ([7200.34; 7235.68]) log units for the annealing scheme and 7224.94 ([7207.16; 7242.71]) log units for the melting scheme).

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Similar(51)

However, if consecutive SNP are in high linkage disequilibrium (LD) with a particular quantitative trait locus (QTL), effects and model frequencies may be distributed across those SNP, and effects and model frequencies of individual SNP will completely capture the effects of the QTL.

Like the environmental temperature variations, the bridge temperatures and model frequencies variations have strong yearly (seasonal) and diurnal trends.

This frequency in turn cannot be ranked with other risk model frequencies as some suggest (Calabrese and Baldwin 2003f), since an independent, statistically acceptable global statistical sampling of all published literature for all dose response models has not been done.

The proposed model is first validated by comparing the model natural frequencies and vibration responses with those obtained from an FE model.

Using the equation model, resonance frequencies and their strengths are first identified.

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