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To test the feasibility of applying leoligin in vivo, we analysed the effects of leoligin in a mouse model for vein graft disease (see Section 2).
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These data suggest parameters for constitutive modeling of veins and may inform the design and testing of prosthetic venous valves as well as vein grafts.
The receiver operating characteristic (ROC) curve for RF model, portal vein diameter, spleen width, platelet count and platelet count/spleen width ratio for the prediction of EV are shown in Figure 1.
Demographic data, severity of liver disease assessed by MELD score (model for ESLD), presence of portal vein thrombosis, and laboratory data were recorded preoperatively.
Therefore, we utilized caudal vein injection as model for hematogenous spread of disease.
In a human saphenous vein organ culture model for graft disease, leoligin potently inhibited intimal hyperplasia, and even reversed graft disease in pre-damaged vessels.
In addition, there are many non vein pixels in the vein image and those pixels are unmeaning for vein recognition.
Surgical trauma during vein harvesting can cause endothelial and smooth muscle injury that has important implications for vein graft longevity.
For vein extraction, information provided by the enhanced image and the vein quality is consolidated using a variational approach.
In an organ culture model for screening agents capable of inhibiting human saphenous vein intimal hyperplasia, leoligin showed a profound inhibitory activity.
The earliest compartment model for cerebral flow considered three compartments representing arteries, veins, and brain tissue (Kellie 1824).
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Justyna Jupowicz-Kozak
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