Sentence examples for model for tuberculosis from inspiring English sources

We successfully developed such a system using the zebrafish Mycobacterium marinum infection model, which is a well-characterized model for tuberculosis progression with biomedical significance, mimicking hallmarks of human tuberculosis pathology.

In this study, this potential was exploited using a zebrafish model for tuberculosis.

During infection of zebrafish embryos with Mycobacterium marinum, a well-established model for tuberculosis, we found that Cxcr3.2 deficiency limited the macrophage-mediated dissemination of mycobacteria.

The lack of a mouse model for tuberculosis that fully recapitulates the disease and the risk of working with the human pathogen owing to its airborne transmission emphasize the need for alternative models.

These results from application of the myd88 mutant in a zebrafish model for tuberculosis illustrate how this mutant could serve as a valuable tool for studying innate immune responses in many other zebrafish models that have been developed in recent years for human infectious diseases, inflammatory disorders and cancer.

Despite the availability of many animal models for tuberculosis (TB) research, there still exists a need for better understanding of the quiescent stage of disease observed in many humans.

The drawback of the standard mouse infection models for tuberculosis is their lack of advanced lesion types as the progression of disease rarely reaches the stages of extensive necrosis and calcification in the lungs [18].

The widely used animal models for tuberculosis (TB) display fundamental differences from human TB.

Recently, Deb et al. developed a multistress dormancy model for M. tuberculosis and showed that M. tuberculosis exhibited all the hallmarks characteristics of dormancy [ 59].

Due to their high similarity (87% sequence identity), the structure here reported can be considered a valuable model for M. tuberculosis FdxC, thus representing a step forward in the study of the complex mycobacterial redox pathways.

It has been used as a pathogenicity model for M. tuberculosis and fluorescent reporters have been previously used in this species [41], [42], [43].