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There was a significant statistical interaction involving sex and race in the model for thyroid cancer.
13 Previously, Claret et al. 28 developed a DPCO model for thyroid cancer that included an empirical model for the first time considering the probability of dose reduction in the context of DPCO frameworks.
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The zebrafish was chosen as a model because fish occupy an early position in vertebrate evolution, and the zebrafish in particular has become an important biomedical model for thyroid-related disease, including obesity, cardiovascular disease, and diabetes [ 35, 36].
When we identified a significant association between ∑PBDEs and a thyroid hormone, we further adjusted the linear regression model for other thyroid hormone levels individually.
Therefore they represent a suitable cell model for investigating thyroid hormone disruption.
Additionally, we transfected normal thyroid cells with SV40 to obtain stable cell lines as previously described (Belge et al. 1995), as a model for normal thyroid function.
In spite of the limitation due to the small number of cases, our observational study has delivered proof of concept for our examination and treatment model for benign thyroid disease.
Also, T3 orchestrates amphibian metamorphosis, thereby providing an exceptional model for identifying thyroid-disrupting chemicals.
We additionally adjusted the models for maternal thyroid parameters.
A comparison of amphibian and mammalian models for detecting thyroid disruption found good concordance in that both detected the majority of 32 environmental chemicals (Pickford 2010).
Additional adjustment of the models for maternal thyroid parameters did not change the results (B additionally adjusted for maternal TSH=−0.87, 95% CI −3.32 to 1.45; B additionally adjusted for maternal free thyroxine=−0.86, 95% CI −3.19 to 1.47).
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