Sentence examples for model for substrate from inspiring English sources

We use family 10 xylanase from Streptomyces olivaceoviridis as a model for substrate specificity of glycoside hydrolases.

This structure allowed a more precise analysis of the active site, generating a more reliable model for substrate binding.

The logistic model for cell growth, the Luedeking Piret model for lipase production and a modified Luedeking Piret model for substrate utilisation were found to accurately predict the fermentation kinetics.

Using the published model for substrate mimicry by the syringolins and knowledge about the substrate preferences of the proteolytic subunits of the human proteasome, we have designed, synthesized, and evaluated syringolin analogs.

On the basis of biochemical and structural studies, we propose a catalytic mechanism for LpxC, suggest a model for substrate binding and provide evidence that mobility and dynamics in structural motifs close to the active site have key roles in the capture of the substrate.

It is, therefore, unknown whether the tetrapeptide is a good model for substrate specificity for 3CLpro.

Although aquo release is central to the widely accepted model for substrate-stimulated O2 activation, we note that simple ligand exchange is insufficient for O2 activation in these enzymes.

We developed two different 3D-pharmacophore models for substrate inhibitors and blockers, which led to the rational design of novel and potent glutamate and aspartate analogues that selectively interact with excitatory amino acid transporters (EAAT).

Based on the metabolism-related protein profiles and cluster analysis performed in the present study, we propose molecular models for substrate recognition of C. cellulovorans in hemicellulose (xylan and galactomannan) and pectin (Figure 6).

The previously published inhibitor-bound complex structures of GlpG (Vinothkumar et al, 2010, 2013; Xue & Ha, 2012; Xue et al, 2012) were useful first approximations for uncovering the structural changes involved in GlpG catalysis, but the small size and chemical dissimilarity of the inhibitors to a polypeptide limited their use as models for substrate binding.

However, this seems unlikely as studies by Brinkworth et al. showed that, when using prediction models for substrates of kinases, the basic amino acids lysine (K) and arginine (R) are often required for optimal recognition of substrates [34].