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Most information on skin DC has been obtained in the mouse model (for review see [4]).
We were also interested in this signaling pathway because of its dual contribution to either oncogenesis or tumor suppression, depending on the cell model (for review, [14]).
Indeed, results from studies in narcoleptic canines indicate an imbalance in brainstem cholinergic and monoaminergic transmission contributes to the expression of cataplexy, as might be expected from this model (for review see [17]).
Additionally, due to the compromised immune system of the athymic mouse, immune-mediated tumor and host stromal interactions important for metastasis may be lost in this model (for review see [ 9]).
Interestingly, in the filamentous fungus Podospora anserina, a well-established ageing model (for review: [ 13- 15]), the accumulation of an O-methyltransferase (PaMTH1) was reported to accumulate in total and mitochondrial protein extracts during ageing [ 16- 18].
Rather, individuals possess a complicated array of masculine and feminine characteristics, that can not be captured by a uni-dimensional (masculinity-femininity) or a bi-dimensional (masculinity x femininity) model (for review see [ 48- 50]).
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Although I do find it odd that so many publications, even if they're online-only, use the same old-fashioned model for reviews as print publications, I'm inclined to disagree: the more the merrier, as far as I'm concerned.
The anterior field of AC is found in many different animal models (for review, see Ref. [30]).
Conception, review literature, design, and modeling for review writing of the paper were done by Mehdi Mirsaeidi.
The review literature, design, and modeling for review writing of the paper were by Mehdi Mirsaeidi and Maham Farshidpour.
This phenomenon termed ischemic pre-conditioning (IPC) has been confirmed in numerous animal models (for review see [ 12, 19]).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com