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After that, we proposed a probabilistic model for probe level adjustment, and the parameters are estimated by MLE.
While exploratory IND studies are extremely useful, further simplification of regulatory processes is necessary, as is the creation of a viable business model for probe development.
Based on these data, we proposed a statistical framework to model the processes of mRNA two-cycle linear amplification, and established a linear model for probe level correction.
Given that this general model for probe summarization lacks terms for adjustment variables, and that statistical inference will be carried out on these summarized values, the goal for normalization remains the same: namely, to remove the influence of adjustment variables on probe intensities in order to maintain their true relationships with the biological variables of interest.
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We thus provide a new experimental model for probing cell-to-cell communication, which we deem the foundation for man-made network architectures involving biological cells.
The finding, reported in tomorrow's Science,* offers a model for probing the causes of a human disorder--familial combined hyperlipidemia (FCHL --that occurs in about 2% oFCHL --thatls in Western countries and can lead to premature coronary disease.
Drosophila ATL has played important roles in understanding homotypic ER fusion mediated by the ATL family, not only because fruit flies serve as a great genetic model for probing the physiological role of ER fusion, but also because it enables a powerful system for studying homotypic membrane fusion in vitro.
These studies introduce a model for probing the mechanisms of reactivation of MTB in vitro.
PUMA is a Bayesian probabilistic model for probe-level analysis that takes into account the probe-level measurement error while estimating the gene expression levels.
A mouse spermatocyte cell line GC-2spd ts), GC-2spd tsecently showhicho be a suitable in vitro model for probing piRNA functions, wes used forecentlyer ashowed
Auditory spatial deficits contribute to impaired spatial awareness in Alzheimer's disease and may constitute a novel perceptual model for probing brain network disintegration across the Alzheimer's disease syndromic spectrum.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com