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Using a biopsychosocial model for obesity, I aim to identify biological, psychological and social modifiable risk factors across the lifespan for obesity and sarcopenia in later life and develop interventions that target these factors.
Two must-reads: Gary Taubes's fantastic Op-Ed questioning the conventional wisdom on salt consumption, and this paper detailing how existing alcohol control policies could be used as a model for obesity prevention.
In this paper, we propose a fractional order epidemic model for obesity contagion.
These strategies can also serve as a model for obesity prevention and control at the national level.
Voluntary wheel running reduces the hepatic TG content in Otsuka Long-Evans Tokushima Fatty rats, a rodent model for obesity and type 2 diabetes [8].
However, marked differences in metabolism and adipose tissue biology between rodents and humans have been recognized and, thus, the pig is emerging as a more appropriate biomedical model for obesity in humans because of its biological similarities with humans [3].
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Of course one has to bear in mind that mice used in this study were of C57BL/6 background which is known to have smaller islet mass and more prominent islet inflammation than other mouse strains, [ 51] but C57BL/6 are a widely accepted mouse model for obesity-associated complications.
In general, miniature pigs become obese when fed ad libitum and are therefore employed as models for obesity and metabolic syndrome.
MJ has developed models for obesity, post-traumatic stress disorder, and depression.
While rodent models for obesity and diabetes are well established [121], [122], here we propose Thoroughbred as a novel in vivo large animal model that may contribute to further insights into the complex molecular interactions that serve to protect against obesity and related pathological phenotypes that are influenced by exercise.
We addressed the potential role of obesity as a confounder by controlling our final multivariate models for obesity status, and we assessed obesity as an effect modifier by running these final models separately for obese and nonobese subjects.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com