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The approach outlined here may also serve as a general model for lineage diagnosis of other groups with a predominant pattern of cryptic diversity.
We have developed a dynamical model for lineage determination: stem cell, trophectoderm and endoderm, for a network whose components are extracted from ChiP-on-chip and microarray data as well as literature studies [9].
We implemented a birth-death process with an uncorrelated log-normal distribution model for lineage substitution rate variation.
GMYC can use either the Yule model (for lineage diversification processes) or the coalescent model (for population-level diversification) and find the respective transition in branching rates between them.
One possible limitation of our study is the fact that the goodness-of-fit of the DR model is better than that of the SRDT model for lineage 1.
I will present our published RelTime method that estimates relative times of divergences for all branching points (nodes) in very large phylogenetic trees without assuming a specific model for lineage rate variation or specifying any clock calibrations.
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Our model for lineage-specific duplication of the major vtg genes in teleosts shows that they comprise a variable subcluster.
Currently, cellular reprogramming through nuclear transfer into oocytes and the use of extrinsic stimuli such as transcription factors or small molecules is widely accepted; thus, future analysis of ribosomal transdifferentiation will provide a unique model for cellular lineage plasticity.
Nevertheless, the mismatch distribution analyses did not reject the sudden expansion model for this lineage.
Taking all the results in the present study and past findings together, we propose a model for hematopoietic lineages at the larval stage of B. mori.
The sudden expansion model was rejected for lineage I (P < 0.05).
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