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Fibroblast spheroids emulate the tissue surrounding tumours and metastasis and hence represent a valuable model for invasion and tissue remodelling.
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There is, however, little known about the morphological, molecular and biological variation within cell lines used as models for invasion and metastasis.
Unfortunately, the morphological, molecular and biological variation within cell lines used as models for invasion and metastasis are not well understood.
One factor that reduces the value of horticultural plants as models for invasion is the limited regulation of the horticulture trade in the USA.
This work is part of an INRA-BBSRC funded project entitled 'Epidemiological and evolutionary models for invasion and persistence of plant diseases.' FMH also acknowledges partial funding from Agropolis Fondation and the INRA SPE Department.
The harlequin ladybird, Harmonia axyridis, has emerged as a model species for invasion biology, reflecting its remarkable capacity to outcompete native ladybird species when introduced into new habitats.
The harlequin ladybird, multicoloured ladybird or Asian ladybird beetle (Harmonia axyridis) is a model species for invasion biology, because it can successfully outperform native ladybird species when introduced into new habitats [ 1].
This paper outlines a conceptual model for the invasion of exotic plants, highlighting the connectivity between road and stream networks provided by geomorphic processes in steep forested landscapes.
Although our results are consistent with a multi-factorial model for tissue invasion, the inherent biological limitations of the study (e.g. the absence of a salivary gland cell line) necessitate caution to avoid overextending the interpretation.
To evaluate biological effects of CTGF on glioma cell invasion through physiologically and anatomically relevant tissue, we determined whether RNA interference-mediated depletion of CTGF inhibits the invasion of GFP-expressing SNB19 and U251 human glioma cells into vital rat brain slices, a well-established organotypic model for glioma invasion.
Fibroblast cells (passage 3 passage 9) were seeded onto dermal composites at 1 × 10 cells per composite ring (see the section 'Reconstructed skin model of invasion' below for further details).
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