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The exposure of CdSe quantum dot on enterocyte-like Caco-2 cells as a model for intestine epithelium was investigated.
Out of the 13 tissues shown in Table 1, there is only one whose best log Kt:p-predicting model was not used to fill in the corresponding descriptor values in the Vss-target dataset, namely the model for intestine.
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Accordingly, we performed FACS analysis of the enterocyte culture model for immature fetal intestine (H4 cells) and the mature intestine (Caco-2 cells).
As observed in the fetal intestine, H4 cells expressed robust TLR4 on the cell surface (Figure 6A) but the surface expression was significantly diminished in Caco-2 cells, an enterocyte model for the mature intestine (Figure 6B).
We used a small intestine model for this study because it is an organ especially sensitive to hemorrhage injury, responding within 1 hr [ 3, 4].
In C. elegans, the polarized epithelial intestine offers an established model for studying intracellular membrane trafficking and vesicle exocytosis (McGhee 2007).
Kishke is Yiddish for intestine or gut, the casing that gave its name to the dish.
However, the Hippo pathway appears indispensable for intestine tissue regeneration.
This intestine transcriptome can serve as a reference sequence database for intestine comparative transcriptome analysis in fish.
Ascaris suum provides a powerful model for studying parasitic nematodes, including individual tissues such as the intestine, an established target for anthelmintic treatments.
Based on the present knowledge of the effects of rotavirus (RV) infection on the physiology of the intestine at different levels of organization, a working model for the pathogenesis of RV diarrhea is presented in the chapter.
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