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The work has resulted in the development and description of basic elements of a unified and integrated model for integrative treatments of People with Multiple Sclerosis that focuses on process-oriented factors and the strengthening of the patients' resources and competences on a physical, an emotional and a cognitive level.
The nematode Pristionchus pacificus is an established model for integrative evolutionary biology and comparative studies with Caenorhabditis elegans.
This study brings us one step closer to the broad goal of developing Prochlorococcus as a model for integrative systems biology — i.e. to understand its cellular architecture, variability, and the forces that shape the Prochlorococcus meta-population in the global oceans.
A model for integrative medicine (IM) adapted to Swedish primary care was previously developed.
Jonas et al. [ 72] document an evaluation model for integrative care specifically for cancer but equally applicable to understanding and evaluating IHC in primary care.
Matched DNAm-mRNA data for 463 ER+ breast cancers from the TCGA and for all FEM genes which were either significantly differentially methylated or differentially expressed, or both, were used as input to a joint latent variable model for integrative clustering using the iCluster R package [ 17].
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Combining evo-devo and ecological approaches can bring a more comprehensive understanding of organismal diversity To allow integration, models should provide a clear ecological context together with tractability to developmental genetic tools The semi-aquatic bugs are good models for integrative studies The approach used in semi-aquatic bugs can be generalized to other models.
Key points Combining evo-devo and ecological approaches can bring a more comprehensive understanding of organismal diversity To allow integration, models should provide a clear ecological context together with tractability to developmental genetic tools The semi-aquatic bugs are good models for integrative studies The approach used in semi-aquatic bugs can be generalized to other models.
This multitude of topics makes them an ideal model system for integrative research toward understanding why and how organisms diversify, offering the opportunity for integrating across disciplines, from genome organization through genes, molecular and developmental mechanisms to phenotypic and ecological effects.
The purpose of this paper, written at the end of the project, is to present an overview of the main steps in the collaboration process that resulted in the construction of an integrative MS treatment model, providing an over-arching framework for integrative treatment within the area of MS care.
NCEAS provided a successful and cost-effective model for doing integrative, interdisciplinary science and similar centres are needed to tackle pressing scientific and environmental issues.
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