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GWA analysis was performed using a logistic regression model to test for associations of each SNP with IS under an additive model (for imputed SNPs, estimated allelic dosage was used).
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A model for imputing the values of factors in new collections of tissue samples even though these samples may originate from different groups and at different times.
The simulation design described in this section relates to a setting where the ideal imputation method is unclear: the presence of x and x in the analysis model means it is difficult to find a compatible model for imputing x| y[ 35].
Some, for instance, hinge on estimates and assumptions about the future, others on imperfect models for imputing monetary values to nonmarket assets.
To produce matrices at the zonal level, ETISplus made a synthetic split using GDP and population data, so that to some degree estimating a trade model at this level is remodelling the model used for imputing the trade flow data.
We added imputed allele dosages and proxy SNPs to the logistic regression model one-by-one, both with and without the corresponding correlated SNP in the original model (see Table S2 for imputed dosages and Table S3 for proxy SNPs).
The variable selection algorithm may easily produce different models for different imputed data sets.
After running separate mixed effects models for each imputed data set, we used PROC MIANALYZE to combine the results.
Although we observed a significant difference between groups (p = 0.040), it did not remain significant when the model was imputed for the respondents who did not chose a particular model of practice (p = 0.074).
Body mass index was by far the most frequently missing information (9.5% missing data) however no differences in obesity as a predictor were observed for models using imputed and non-imputed data.
Multiple imputations were used for models where imputed cholesterol was used in creating the weights.
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CEO of Professional Science Editing for Scientists @ prosciediting.com