Sentence examples for model for eoc from inspiring English sources

To further characterize the role of the NCAM/FGFR complex in EOC dissemination to distant organs, SKOV3 cells were injected intraperitoneally into immunodeficient mice, a widespread model for EOC peritoneal metastasis (Arlt et al, 2006; Donahue et al, 2011; Shaw et al, 2004; Slack-Davis et al, 2009).

The reviewers had the following modest concerns, questions and requests: A. Theory:1) Sphere model for Eoc h.

The authors choose a sphere model for Eoc, which is reasonable for cases in which the diffracting range is dominated by energy dispersion and unit-cell variation.

In our mouse model of EOC, IL-2/IL-15 signaling was critical for CD8+ T-cell proliferation and function in ascites [8].

To this end, we previously developed a mouse model of EOC that allows functional assessment of CD8+ T cell responses in the ovarian tumor environment [8].

We recently demonstrated in a murine model of EOC that the ascites environment can be highly permissive to T-cell proliferation [8].

Previous work in our laboratory has involved the generation of novel drug resistant models of EOC as part of an ongoing programme to understand the basis for chemoresistance in this disease.

Here we show for the first time in EOC that, by using siRNA specific for ChoK-alpha, the expression and the activity of the enzyme can be downmodulated in two models of EOC affecting cell behaviour and sensitivity to drug treatment.

Furthermore, by employing mouse models of EOC development, we observed that the NCAM/FGFR interplay promotes both local invasion and metastatic dissemination of EOC to organs of the peritoneal cavity.

Our group has previously demonstrated that automated analysis of IHC can identify new prognostic subgroups [ 15- 17], and automated analysis was used in this study to develop a quantitative scoring model for HMG-CoAR expression in EOC.

To identify suitable in vitro models for functional analyses, EOC cell lines were screened for SOX11 expression and promoter methylation was assessed in both positive and negative cell lines.