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Sec61β from S. pombe appears as an interesting model for elucidation of the cellular roles of a highly conserved TMD present in every living kingdom.
The fission yeast Schizosaccharomyces pombe has well characterized regions of heterochromatin and has proven to be a powerful model for elucidation of epigenetic silencing mechanisms.
Most are derived from metastatic sites and thus may not represent the best model for elucidation of early indicators of cancer formation [ 17- 19].
S52P TTR variant provides a unique model for elucidation of the pathway of TTR amyloidogenesis primed by proteolytic cleavage of the 48 49 peptide bond.
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An illustrative case study taken from Ref. [1] is studied to demonstrate the proposed transshipment models for elucidation of the hybrid power system.
In this review, we have critically evaluated recent progress in seven fungal species which are well-studied models for elucidation of pathogenicity determinants of animal and plant hosts.
The epidermis-barrier function against invading pathogens and the wound-repair pathway appear to be evolutionarily well conserved between mammals and Drosophila, indicating that Drosophila would likely serve as a sophisticated model system for elucidation of the molecular mechanisms underlying mammalian skin disorders.
These T-IhNSC line provides a versatile model for the elucidation of the mechanisms involved in human neural stem cells expansion and for development of high throughput assays for both basic and translational research on human neural cell development.
Bryophytes were the first land plants and they have been a powerful experimental tool and model for the elucidation of complex biological processes [ 9- 11].
Thus, it is ideal to use the medaka as an animal model for the elucidation of genetic factors underlying complex traits (Kimura et al. 2007).
Our demonstration of both phenotypic and molecular conservation of developmental ethanol effects between flies and mammals indicates that Drosophila is a good model for further elucidation of the mechanisms of action of developmental ethanol exposure.
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