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Pluripotent stem cells are an efficient model for differentiation and have been directed towards both white adipogenic and brown adipogenic lineages.
The influence of laminin-111 (Lm111) and its integrin and dystroglycan (DG) receptors on epiblast in embryoid bodies (EBs), a model for differentiation of the embryonic plate, was further investigated.
A typical model for differentiation adopts bistable dynamics in which transitions between states are driven by noise (e.g., [ 22]).
We report on the establishment of a model for differentiation induction in sarcomas, using the clonal rhabdomyosarcoma cell line BA-HAN-1C.
A well-known in vitro model for differentiation studies derived from rat pheochromocytoma, the PC12 cell line, is used to investigate the potencies of polyphenols on neurite outgrowth.
The current model for differentiation supports a co-ordinated process whereby inhibitors of differentiation are down-regulated prior to up-regulation of factors necessary for myelin gene transcription (Li et al., 2009).
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In further evaluating the potential value of spectra generated from tumour tissue for classifying various clinic-pathological characteristics of disease, we observed low ROC errors with the kNN predictive models for differentiation (0.171) and disease recurrence (0.105).
The extension to our theoretical model allows for differentiation by patient's severity, showing how hospitals manage their lists when having to treat both milder cases, and more severe ones that require more attention and resources.
D1 (NT2) cell line is one of the characterized hEC cell lines used as a model system for differentiation of cells from the neural lineage [for review see [7]].
These characteristics of ES cells make them a valuable model system for differentiation study and cell-based regeneration therapies.
These results suggest that microarray analysis of chemical-induced spore formation is an excellent system to specifically identify genes necessary for the core sporulation process of a Gram negative model organism for differentiation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com