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Using a model for catalysis of a dynamic equilibrium, the role of constraint in catalysis is quantified.
A model for catalysis based on selective energy transfer from catalyst to the reactant is applied to some reactions catalyzed by zeolites or zeolite-related systems.
The combined data therefore suggest a model for catalysis in which the mRNA is drawn into the active site by electrostatic forces from several basic side chains, while Y87 and 16S rRNA C1054 orient the substrate correctly for a nucleophilic attack of the 2′-OH of the second nucleotide in the A site on its own 3′-phosphate.
This kinetic model for catalysis includes two sequential mechanisms, dependent on the amount of iron available to the protein and the concentration of electron acceptors (dioxygen) for the oxidation step, and a new intermediate in the catalytic reaction (a putative hydroperoxodiFe(III) complex).
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This is analogous to the conformational sampling model for enzyme catalysis, in which the rate of catalysis depends on the probability of achieving a subset of protein conformers that can promote high rate accelerations.
The present work proposed a new mesoscale model for heterogeneous catalysis, based on conservation relationships and a stability condition that was built from the principle of compromise in competition.
Potential explanations for these results are discussed, and a revised model for SrtA catalysis is presented.
The crystal structure of bovine F1 revealed remarkable asymmetry in the conformation and nucleotide occupancy at the α β interfaces, consistent with the binding change model for rotary catalysis (Boyer, 1993; Abrahams et al, 1994).
Mak, C. H., Pham, P., Afif, S. A. & Goodman, M. F. A mathematical model for scanning and catalysis on single-stranded DNA, illustrated with activation-induced deoxycytidine deaminase.
Unlike animals, plant cells contain three evolutionary distinct genomes; nuclear, mitochondrial and chloroplast, thus providing a unique model for investigating mC catalysis and biological function.
We use this model to predict residues essential for catalysis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com