4T1 tumour cell line, a recognized model for breast cancer studies originally isolated by Miller and colleagues57,58 was exploited.
We illustrate the application of these ideas in the setting of a natural history model for breast cancer.
The proposed system provides an effective classification model for breast cancer.
Dunne, L. W. et al. Human decellularized adipose tissue scaffold as a model for breast cancer cell growth and drug treatments.
The similarly injected control K19-tva mice developed mammary tumors exhibiting high metastasis to lung, making this an ideal model for breast cancer metastasis.
W.Y. Cheng, T.H. Ou Yang and D. Anastassiou, "Development of a prognostic model for breast cancer survival in an open challenge environment," Science Translational Medicine, Vol. 5, Issue 181, p. 181ra50 (2013).
ChIP-exo mapping of Pol II, a histone variant, and select histone modifications should enable other investigators to use these data sets for their own research to further understand the detailed interplay of Pol II and chromatin in ultra-high resolution in a preclinical model for breast cancer.
Thus, it is essential to develop a tailored model that unravels breast cancer mechanisms by identifying disease-specific functional units of biological pathways and apply the model for breast cancer prognosis.
Now, instead of trying to make sense of a black-box model for breast cancer prediction, which could help millions of patients across the globe, machine intelligence could provide a model that's entirely transparent about why it's generating that prediction.
An ideal model for breast cancer metastasis studies should be useful as a tool to study the entire metastasis process of cancer cells (Xia et al. 2012).
Song et al. have successfully presented QD-based quantitative high-content imaging cytometry as a new model for breast cancer prognosis and classification [59].
