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In a pre-clinical animal model for bladder cancer, free particles were instilled in bladders with pre-established tumors.
The in vivo mouse model for bladder cancer is particularly well suited for T1- and T2-weighted MRI.
In this study we compared the regeneration of bladder tissue with a collagen-based biomatrix in a sheep model for bladder exstrophy with bladder tissue regeneration in normal bladder.
If further studies corroborate the important role of Capn3 in urothelial tumors of the urinary bladder, cattle with urinary tumors may prove useful as animal model for bladder carcinogenesis.
Using an animal model for bladder cancer, β-catenin was shown to induce tumorigenesis, and androgen-mediated AR signals appeared to synergize with β-catenin [ 93].
To date, the BOO model is the prominent model for bladder dysfunction, and other several pathologic models are in challenging state.
Similar(46)
It is also worth to remember that the establishment of reliable and reproducible animal models for bladder cancer remains an ongoing challenge, since developing therapeutic agents requires in vivo models [47].
The rabbit model is suitable for bladder tissue engineering studies as it is an easy model to use.
In this study, the adhesive interaction between poly methylidene malonate 2.12) or PMM 2.1.2 microparticles and collagen, which serves as the model extracellular matrix for bladder wall, was probed with confocal reflectance interference contrast microscopy (C-RICM), single-particle compressive force measurement and contact mechanics theory.
The bladder cryoinjury can be used as a model for studying impaired bladder compliance and detrusor contractility as well as treatments that may improve bladder function such as tissue engineering.
We have therefore developed an in vitro model of bladder cancer invasion using de-epithelialized rat bladder to allow for tumour cell extracellular matrix interactions.
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