Sentence examples for model for autoimmune from inspiring English sources
Our previous finding of decreased septin 7 expression in blood-derived lymphocytes in ERU, a spontaneous animal model for autoimmune uveitis in man, extended the role of septin 7 to a potential key player in autoimmunity.
ERU represents the only spontaneous model for autoimmune uveitis in humans8 and is characterized by remitting painful attacks of the inner eye, caused by infiltration of immune cells9, eventually leading to vision loss.
An acute transfer model for autoimmune diabetes was employed by introduction of fluorescently labeled splenocytes harboring diabetogenic TCR-transgenic CD8 T cells into recipients expressing both antigen and GFP in their beta cells.
Although EAN is a representative model for autoimmune diseases of peripheral neurons, experimental autoimmune encephalomyelitis is a representative model for autoimmune diseases of the CNS and is a model for human multiple sclerosis.
The Smyth line (SL) chicken is the only animal model for autoimmune vitiligo that spontaneously displays all clinical and biological manifestations of the human disorder [ 2, 3].
The NOD mouse is a valuable experimental model for autoimmune diabetes; it possesses I-Ag7 as the sole class II molecule [ 55].
He subsequently came to Columbia University where he is developing transgenic mice to serve as potential models for autoimmune diseases.
CD4+CD25+FOXP3+ regulatory T cells (Treg) are of critical importance for the maintenance of immune homeostasis, as numerous experimental mouse models for autoimmune diseases correlate the presence of functional Tregs with amelioration of disease severity [1], [2].
Targeting the interaction between ICAM-1 and LFA-1 as a treatment for (auto immunity has been the subject in a number of studies (reviewed in [17]), and was shown to have beneficial effects in animal models for autoimmune diseases [9], [10].
Experimental mouse models for autoimmune diseases obviously cannot entirely mimic human diseases.
This might suggest shared disease pathways in different models for autoimmune diseases controlled by the same genes within this interval.
