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By inverse simulations, generally good model fits are derived.

The adsorbed P fraction of the LCF model fits are operationally defined as adsorbed TPP.

Phosphorus reference spectra used in the LCF model fits are located in the (Additional file 1: Figure S1).

Representative TACs generated from model fits are shown overlayed on the relevant measured data in Fig. 3.

In Table 4, the model-derived fractional blood volumes obtained from the model fits are compared with ICRP 106 values and with the original FDG model values.

Considering R 2, the model fits are relatively good, at 0.62 0.76, and is as good as for the models provided by Cha (1998).

Model fits were compared by F tests.

The model fits were compared using likelihood ratio test.

Model fits were checked by examining partial residual plots.

Model fits were compared using Akaike information criteria (18).

Model fits were acceptable (R-squared = 0.923 and 0.978).