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As an indication of poor model fit, implementation of the animal model DHGLM gave a lower adjusted profile h-likelihood (see next section "Model selection") than an animal model without heterogeneity of residual variance.
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Overall, we achieved a final well-fitting model (CFI = 0.933; TLI = 0.918; RMSEA = 0.045; SRMR = 0.048) and explained approximately 24% of the total variation in implementation effectiveness.> -wrap-foot> Model Fit Statistics: CFI = 0.933; TLI = 0.918; RMSEA = 0.045; SRMR = 0.048.
However, the between-subject variability could be removed after implementation of between-dose occasion variability without a major impact on the model fit (ΔOFV = 1.94).
Figure 2 shows that a quadratic term may be required to improve model fit, but GEE does not provide a goodness-of-fit test with, for instance, the SAS© implementation.
Fig. 8 Model fit.
Model fit (R2=.6468) is acceptable.
The implementation of a lumefantrine or desbutyl-lumefantrine drug effect (Emax and sigmoidal Emax) on the constant hazard model did not improve the model fit significantly.
b: Overall model fit statistics.
The model had satisfactory model fit.
Model diagnostics showed adequate model fit.
All the fit indices suggested a reasonable model fit.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com