We validated these model findings with additional experiments on mouse liver sections.
To determine whether our animal model findings were clinically relevant, we mined expression data from 99 patients from The Cancer Genome Atlas (TCGA) for a potential association of Lgl1 mRNA expression levels and glioblastoma patient survival.
Additionally, we present a methodology to implement the model findings, which allows to verify its accuracy in practice.
Comparisons between model findings and available experimental data are presented to assess the accuracy of the proposed numerical model.
The model findings are related to observations of the forest tent caterpillar offering insight into this host parasitoid response to habitat structure.
Our model findings are relevant for any ecological indicator data with similar properties, and the evaluation approach is applicable to any monitoring program.
However, as the system of control strategies is overdetermined, our model findings suggest that a crouched leg posture does not necessarily enhance running stability.
The numerical model is then employed to investigate the effects of up-scaling of laboratory model findings to a full-scale contact tank.
Accordingly, increasing the spatial core of inexcitable tissue decreased the frequency of rotation, widened the excitable gap, and enabled an external wave to impinge on the rotor core and displace the source.These model findings highlight the importance of structural features in rotor dynamics and suggest that regions of fibrosis may anchor fibrillatory rotors.
The consistency of our urge model findings with prior studies investigating the suppression of blinking and other bodily urges, thoughts, and behaviors suggests that a similar investigative approach may have utility in fMRI studies of disorders associated with abnormal urge suppression such as Tourette syndrome and obsessive compulsive disorder.
The model findings indicated that the developed mechanistic model for the roller compactor can provide a design space to correlate the process parameters and materials properties to the critical quality attributes of granules which would be useful for implementation of Quality-by-Design paradigm in pharmaceutical manufacturing.
