Therefore, our characterisation of established cell lines with the regard to alterations in kinase genes finally provides suitable model systems for preclinical study, particularly in the light of the recent interest for the development of new drugs targeting mTOR/PIK3CA as well as VEGFR activity [ 59].
In a recent "Economic Journal" article, De Vany and a coauthor, David Walls, developed a mathematical model of how filmgoers behave which finally provides a rigorous intellectual basis for the old Hollywood adage "Nobody knows anything".
With today's newly-introduced freemium model, Fleep is finally providing that clarity.
Simulation results of the MPC controller and the simulation model in closed-loop operation finally provide a proof of concept.
The following sections describe the data, the hierarchical and nonhierarchical models, our study and its results, and finally, provide conclusions.
Finally, the model provides a scaffold for modelling carotenoid metabolism in other vertebrate systems for epistemic as well as instrumental purposes.
And finally, our model provides risk estimates incorporating both a more streamlined individual-level risk model, akin to chemical risk models, and a dynamic population-level model that accounts for secondary transmission and immunity.
Finally, the model provides a physical basis for a pressure-dependent yield criterion.
Finally, our model provides the foundation for future cost-effectiveness analyses to evaluate targeted screening and various management strategies for EAC, a pressing clinical and policy issue as there is currently no accepted strategy.
Finally, this model provides a complementary system to genetically engineered mice for studying and validating the function of genes of current clinical interest to the neurooncology community.
