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In the model figure we hypothesize the existence of a polar anchoring protein encoded on the phage genome due to the observation that only phage-infected cells show polar stabilization of filaments and the structural similarities to a bipolar spindle.
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Comparing in general the electrical field profiles obtained from 3D models (Figure 2a,b) with that of the 2D model (Figure 2c), we observed the following: 1.
By constructing an axially symmetric 2D numerical model (Figure 6a), we created a synthetic thermal decay curve simulating the APC-T tool in the sediment that is initially heated by friction and then cooled by thermal diffusion and hydrate dissociation.
For the Simulink model (Figure 3), we added transfer functions from previously published models (see Results) to represent the dynamics of otolith afferent responses and the ocular motor plant.
As illustrated in our model (Figure 9), we suggest that Dazl functions early in vivo or in differentiating mESCs in vitro, either directly or indirectly, to maintain germ cell pluripotency.
In the model figure (currently Figure 8) we represented CENP-A chromatin as a region of which the size is independent of the downstream centromere complex and kinetochore (as based on data in Figure 6).
This is consistent with our previous conclusions, as shown in the model figure (now Figure 8): We proposed that putative human heterozygotes, which have never been documented, are likely not viable, whereas the fly heterozygotes clearly are almost completely healthy.
Finally, we have added a more critical analysis of what our data represented and finished with a model figure to demonstrate what we are proposing as the mechanism by which Angptls may regulate Notch.
We therefore propose a model (Figure 7) in which differentiation genes exhibit progressively less epigenetic constraints.
We have added a model figure.
We also consider the additive model (Figure 1a).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com