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In model experiments, we demonstrate the usefulness of isotopic detection for several high-throughput applications in biology.
Based on relatively simple concepts supported with selected model experiments, we also give several practical recipes that might be helpful for designing of cathodes with improved overall kinetics.
In cell model experiments, we determined that C1q activates ectopic WOX1 in killing DU145 cells.
In accordance with the subcutaneous model experiments, we initiated gemcitabine (100 mg/kg twice/week) treatment on day 10 and added INC280 (10 mg/kg/d) on day 20.
To identify a small set of F. tularensis protein candidates for validation in animal model experiments, we focused on nine proteins that interacted with multiple proteins in both hosts.
Given this, and the agreement between independent estimates of N (and Nt) from satellite observations and AMIP simulations, and from forced ocean model experiments, we suggest that there are likely to be errors in the observational reanalysis of ocean heat content between 2001 and 2007 (grey-shaded region in Figure 2).
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As a model experiment, we targeted integrin alpha V (ITGAV), which is a major transmembrane receptor expressed in almost all the cells, and established ITGAV-overexpressed and -downregulated HEK293 cells for selection and counter-selection, respectively.
In our automated modeling experiment, we decided to minimize the apriori modeling assumptions and consider all 126 model structures as valid alternatives.
In this verification modeling experiment, we swapped the α andβ structural elements in our de novo BPP-1 MCP model to create an interchanged model that matches the HK97 topology.
To compare phenotypic strength between a model and experiments, we used WUS levels as a measure in the models and compared with carpel numbers, which represent an experimental estimate of phenotypic strength, see e.g. [ 9, 15, 19] (Methods).
Through a series of model architecture experiments, we demonstrate that the use of a consistent functional response for all predator-prey interactions, as well as the use of density-dependent mortality rates for planktonic functional groups, are important factors in reproducing annual and seasonal observations.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com