Moreover, the mouse model experiments suggest that the murine host-derived cytokine network replaces human-derived cytokines in stimulation of hormone-independent growth of MCF7S1 breast cancer cells.
Model experiments suggest that the appearance of detectable concentrations of this radical result from a disturbance of the normal state of the ascorbic acid, dehydroascorbic acid redox system.
The exact mechanism of retinotoxicity of CQ and HCQ is not clear; however, cell culture studies and animal model experiments suggest a possible adverse effect on lysosomal function and subsequent lipofuscin accumulation [ 14, 15].
Although models and prior experiments suggest that mass Diameter influences oxygen profiles [3], [5], [10] [12], [29], we found no significant effect of Diameter in laboratory studies (Table 4), either as a main effect or in interaction with other factors (Table 4).
Modeling and laboratory experiments suggest that stones grow over a span of hours in the proper urinary environment and that growth rates are dramatically increased by increasing urinary supersaturation of calcium (Borissova et al. 2010; Costa-Bauza et al. 2005).
DICER-null embryonic stem cells usually do not survive, but several cell-type specific conditional DICER1 knockout models exist and experiments suggest that only a subset of differentiated cells are tolerant to a complete loss of DICER1 (Gonzalez and Behringer, 2009; Iida et al, 2011; Nagalakshmi et al, 2011).
The agreement between model and experiments suggests that the thermal mechanism is the major NO formation pathway.
The agreement between the model and experiments suggests that wettability trends in tight formations can be quantitatively predicted and that the bulk compositions of fracturing fluid and overflush compositions might be individually tailored to increase oil recovery.
The contrast and analysis of the simulation model and the physical experiments suggest that the further correctly modified geometric parameters and boundary conditions according to practical situations can significantly improve the accuracy of the numerical calculation.
Given this, and the agreement between independent estimates of N (and Nt) from satellite observations and AMIP simulations, and from forced ocean model experiments, we suggest that there are likely to be errors in the observational reanalysis of ocean heat content between 2001 and 2007 (grey-shaded region in Figure 2).
Postmortem brain pathology analyses, MeCP2 mouse models and in vitro experiments suggest that MeCP2 regulates axon outgrowth, dendritic spine formation and dendritic arbor complexity (Chao et al., 2007; Chapleau et al., 2009; Cheng et al., 2014; Jiang et al., 2013; Jugloff et al., 2005; Lombardi et al., 2015).
