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As a model experiment, we targeted integrin alpha V (ITGAV), which is a major transmembrane receptor expressed in almost all the cells, and established ITGAV-overexpressed and -downregulated HEK293 cells for selection and counter-selection, respectively.
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For the numerical model experiments, we use the standard configuration of a global coupled ocean-atmosphere model, the Climate Forecast System version 2 (CFSv2).
Using long-term observations and coupled model experiments, we provide compelling evidence that the enhanced Indian Ocean warming potentially weakens the land-sea thermal contrast, dampens the summer monsoon Hadley circulation, and thereby reduces the rainfall over parts of South Asia.
Using observations and climate model experiments, we demonstrate that this reduction in rainfall is linked to the rapid warming of the Indian Ocean, especially its western part, during the past century.
In model experiments, we demonstrate the usefulness of isotopic detection for several high-throughput applications in biology.
Based on relatively simple concepts supported with selected model experiments, we also give several practical recipes that might be helpful for designing of cathodes with improved overall kinetics.
"Through our computer model experiments, we wanted to see if we could predict under what conditions these bubbles can form," Falk said.
In cell model experiments, we determined that C1q activates ectopic WOX1 in killing DU145 cells.
In accordance with the subcutaneous model experiments, we initiated gemcitabine (100 mg/kg twice/week) treatment on day 10 and added INC280 (10 mg/kg/d) on day 20.
To identify a small set of F. tularensis protein candidates for validation in animal model experiments, we focused on nine proteins that interacted with multiple proteins in both hosts.
Given this, and the agreement between independent estimates of N (and Nt) from satellite observations and AMIP simulations, and from forced ocean model experiments, we suggest that there are likely to be errors in the observational reanalysis of ocean heat content between 2001 and 2007 (grey-shaded region in Figure 2).
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