We have addressed the question of the number N of data points required to compute a model (an expansion) to degree d with an empirical point of view; indeed, not only the distribution of data points, but also the noise intervene in a broad sense, on the data.
These pilot projects are often successful - the challenge is to have them accepted as a model for expansion to larger areas, or even reproduced nationwide -and to have them work well without the intensive support usually granted to pilot projects.
The model required expansion to distinguish these components from response shift and to differentiate response shift phenomena as initial responses to catalysts from those that reverberate or continue the process (feedback loop).
Another avenue for model expansion is 'upstream' to the present model in developing detailed quantitative description of AT1R mediated signaling pathways.
Such business challenges may be met through planning and design that considers the long-term costs of training, support, and maintenance; revenue generation and licensing by instituting processes which support communication and interactions; and by employing software technology which enables easy model expansion and re use to gain an economy of scale and reduce development costs.
Together these data and model expansion can be used to examine systemic changes and therapeutic responses; thus, advancing angiogenic targeting for predictive medicine.
CellML 1.1 has been developed to extend the component-based architecture of CellML 1.0 to facilitate model expansion and re-use.
It was found that, when applied using a powerful and flexible modelling environment, the component-based modelling concept provides not only an elegant method for model development, but also the opportunity to explore model expansion and refinement through use of transplantable components.
In addition, the IBIS model would need expansion to handle the risks of women with atypical hyperplasia, since the model is not recommended for these women due to its poor discriminiation among them (AUC 0.54) [ 38].
Benefits of using the PNSRL model include: Integration expansion to allow for relationships to other integrations.
