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Moreover, the impact of possible measurement variability on model estimate has been performed by using Monte Carlo simulation using normal distribution (Baughman et al. 2010).
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The model estimates have typically been validated using experimental data from bio-monitoring.
Secondly, the ITS model estimates have not been controlled for covariates.
Therefore, multipollutant model estimates had larger standard errors and smaller posterior probabilities of being greater than zero than their single-pollutant counterparts.
The bigger problem though was that, until now, modelling estimates have been based on a discredited technique, commonly referred to as "input-output analysis".
In Rasch models, each ability estimate has an associated standard error of measurement (SEM).
As an alternative to the binomial mixture model estimate, we have also included the Chao lower-bound estimate [ 11] when fitting to real data.
A new design model, providing better estimates, has been suggested at the end.
The Glazers' leveraged business model, estimated to have cost United £680m in interest and fees since they took over in 2005, requires consistent success on the pitch to keep the global sponsorship deals rolling in and the tills ringing.
Second, though its assumptions are weaker than parametric models, model estimates still have good statistical properties, and the efficiency of statistical tests does not suffer greatly.
Model-derived estimates have been proposed for quinine in uncomplicated falciparum malaria (42).
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