However, the model envisioned that the three charged side chains replaced in the superclamp mutant (D27, E34, and R37) insert into the hydrophobic groove left in the SNARE complex, which is very unlikely from a thermodynamic point of view.
In case covariates other than size and/or age are identified in a pediatric covariate model, we envision that the complete covariate model describes the biological system and that therefore this complete covariate model should be extrapolated between drugs.
GM envisions that hydrogen could be its savior, disrupting the economic model that has strangled it for the last 40 years.
In this model, we envision that Ash2L/RbBP5 and MLL1SET may come together to form a complete catalytic center in the MLL1 complex, each providing essential features to ensure optimal alignment of substrates for catalysis.
Considering the evolutionary conservation of all the proteins implicated in this model, we envision that the process may be operating at some target genes in other eukaryotes.
With the emergence of two monocyte subsets, a multistep model would envision that the relative surface expression of adhesion molecules and chemokine receptors determines the recruitment behaviour of each subset.
Almost without exception, recent climate models envision reductions that range from the modest to the catastrophic by the second half of this century.
In the simplest version of his model, Frank [ 13] envisions that each individual has two quantitative traits, policing and competition.
As such, the PSF represents the nearest approximation to the primary care model envisioned at Alma-Ata that is currently implemented by a major developing country, and may be an example to be emulated by other such countries.
The model envisions a message source — an idealized user with clear intentions — passing through a noisy channel that introduces typos by omitting letters, reversing letters or inserting letters.
