Molecular modeling elucidated an expected binding mode of 4b with Mer TK and necessary interactions between them, thus supporting the hypothesis that Mer TK might be a biologic target of this kind of new active compound.
A model elucidates two transport mechanisms associated with the volumes dissolved electrolytes occupy: the 'excluded-volume effect', which arises when concentration polarization induces solution-density gradients that drive volume redistribution; and 'Faradaic convection', which occurs when interfacial electrochemical reactions induce bulk flow.
The model elucidates the effect of glutaraldehyde, a crosslinking agent, on the release profile in terms of the initial drug distribution, diffusivity of the drug, degradation rate of gelatin and its ability to form polyionic complex with the drug.
A finite element model elucidates how incorporation of the isotropic medium for focal point sequestration recovers an order of magnitude in sensitivity.
Over the course of a day and a half, the partnership model elucidates the drivers behind each company's desire for partnership, allows managers to examine the conditions that facilitate or hamper cooperation, and specifies which activities managers must perform to implement the relationship.
Since there is a growing evidence suggesting association between CD, intestinal cancers and other diseases, we took advantage of the rhesus macaque model of gluten sensitivity to elucidate A) if such relationship can be detected on the gene expression level, and B) if changes in dietary gluten intake influence selected gene expression.
Our model also elucidates a possible overlap of the two pathways through the events –18q and +8q.
The model elucidates the complex spatiotemporal processes occurring within the washcoat and along the reactor length.
The proposed model elucidates the release of hydrophobic RA from hyaluronan-derivative biomaterials.
Our model elucidates that changes of the functional system occurred at the macroscopic and the microscopic level.
