Sentence examples for model disorders from inspiring English sources

The hypothesis is that altered postnatal maturation/survival of subsets of inhibitory neurons in cortico-basal ganglia circuits causes specific alterations in synchronous neuronal firing that may model disorders of the TS spectrum.

To model disorders of cortical development in a human system, the lab has recently adopted the induced pluripotent stem cell (iPSC) model and has developed a new way to derive cortical organoids from iPSCs as a window into normal and abnormal neuronal development (Mariani et al, 2012).

When all characteristics related to health were entered into the multiple logistic regression model, disorders of the low back and sick leave due to reasons other than disorders of the neck, shoulders and/or back remained significant (Table 5).

When all variables from the three models were entered into the final model, disorders of the low back during the preceding 12 months (OR: 1.95; CI: 1.23 3.10) and sick leave during the 12 months preceding baseline (OR: 6.61; CI: 4.08 10.73) were the only factors predicting sick leave due to any cause after 18 months.

Schizophrenia may therefore qualify as a model disorder to test neural correlates of gesture impairments.

Our model disordered medium mimics an open fracture by a Hele-Shaw cell with a two-valued gap spacing randomly distributed in the fracture (or Hele-Shaw) plane.

Pseudoatrophic brain changes are often readily visible in individual brain scans, and AN may be a valuable model disorder to study structural neuroplasticity.

We used linear regression to model disorder content as a linear function of number of related diseases for a gene, number of related disease classes for a gene, and gene degree in DGN.

Open image in new window Fig. 7 Normalized system responses for different irregularities under double-clamped simple shear loading; left: beam models, right: Cosserat continuum models; disorder-dependent Cosserat parameters as in Fig. 4.

In both the clamp and the flanking models, disordered regions near the interacting protein segments (often short peptide motifs) contribute to binding by influencing affinity and specificity.

Overexpressing mutant human transgenes in mice may poorly model the disorder or disorders that characterize the vast majority of AD patients.