In his recent publication The New Harvest -- a memo for African presidents -- Juma advocates for a relentlessly holistic model of development, whereby infrastructure, education, technological innovation, and entrepreneurship interact and co-evolve across borders.
We propose a de novo DNA methylation model during germ cell development whereby a pattern is established by long-range chromatic interactions through syntenic repeats combined with regional methylation spreading from methylation associated SNP clusters.
Based on this work a model was developed, whereby SeqA occludes TnsE's access to the replicating chromosome.
Instead, the "connectivity model of muscle development" is proposed as a mechanism for muscle development: whereby the closer to the myofibril core of muscle cells, the greater the gene expression changes during muscle differentiation and the greater the muscle specificity.
A split sample approach was used, whereby 80% of the patients were randomly selected for model development and the remaining 20% were used for model validation.
(B ) Hypothetical model for the biochemical role of CED-3 cleavage in protein turnover during development whereby a new N-terminus is generated which could potentially destabilize the protein according to the N-end rule (see text).
Dorsal closure (DC) is an essential step during Drosophila development whereby a hole is sealed in the dorsal epidermis and serves as a model for cell sheet morphogenesis and wound healing.
A major cause was infill development whereby gardens were built over.
A history of mesoscale model development.
Next up: quantitative model development and validation.
