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Environmental model development requires both scientific understanding of environmental phenomena and software developer proficiency.
Model development requires realistic hurricane wind and storm surge representations to the proper spatial and temporal scales.
The use of field plot data for model development requires co registration of field plot location with the ALS data [16,17].
Model development requires a multidisciplinary approach.
The use of field plot data for model development requires co registration of field plot location with the ALS data [ 16, 17].
Moreover, successful model development requires substantial experimental data collection and strategic contributions from a variety of functional experts (e.g., pharmacology, biology, clinical research, biostatistics, mathematics).
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We discuss the outstanding policy questions which models can be used to answer and the data and model development required to address them.
Numerous competing models have been proposed for this process but experimental validation and guidance for further model development require new experimental approaches capable of resolving local stresses within the dislocation microstructure.
Successful analysis of the models used in Model-Driven Development requires the ability to synthesise the results of analysis and automatically integrate these results with the models themselves.
Namely, modeling BBB development requires cells with an embryonic phenotype, whereas modeling BBB maintenance and constructing a model for drug screening would require cells with a mature adult phenotype.
While modeling BBB development requires embryonic neural cells and immature BMECs, modeling adult BBB maintenance requires mature BMECs along with co-cultured cells of the adult neurovascular unit such as pericytes, astrocytes, and neurons.
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