49 Our model development methods were as follows.
Our model development methods followed established time series forecasting procedures.
Current model development methods can be generally characterized as manual, semi-automated, or automated.
Valuable personal impression was evaluated and a final set of potential models was recommended, according to the given soft criteria (see subsection Procedure of model development (Methods)).
Step 4. The remaining 26 institutions were ranked on the given data and the criteria of general conditions (see subsection Procedure of model development (Methods)).
With the aim of facilitating the development of service oriented solutions, we propose the specification of an architecture centric model driven development method.
This paper introduces the development of such a database, including the determination of its design requirements, the selection of its database management system, the creation of its database model, its development method, and the details of its sub-databases for composite materials, functionally gradient materials, and heterogeneous materials with a periodic microstructure, respectively.
To initialize the model development, preprocessing methods are performed.
DR assisted with model development, research methods, and editing of the manuscript.
Other items that, in our opinion should be taken into consideration with regard to the data-synthesis are: study quality, variables used for model development, statistical methods used for variable selection procedures, the performance of models, and sufficient cases and non-cases to guarantee adequate study power.
For a more detailed description of the model development, see Methods and Additional file 2. A key component of the model is that it incorporates both tumor cells and tumor endothelial cells, and these cells can express both the ligands and receptors of the VEGF and Sema pathways.
