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A state-of-the-art model developed more than 25 years ago by Sorensen already included such details for the distribution, metabolization and excretion dynamics of glucose, insulin, and even glucagon, which is neglected in most other models.
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Mouse models developed more recently have implicated LGI1 in neuronal maturation processes.
Furthermore, this model has been the reference for other models developed more recently.
A similar model has been developed more recently by pairing a p53 mutant allele with an Nf1 allele flanked by loxP sites (a so-called floxed allele).
These data-driven models can be developed more quickly with less expense.
The second model, developed much more recently, uses the theory of dissociation and reaction.
The modified DRASTIC model developed a more accurate vulnerability map by adding the two parameters: land use and lineaments.
The fuzzy outranking preference model developed is more suitable to be used for concept selection in the imprecise and uncertain design environment.
These simple models were validated by leveraging previously developed, more complex models for rotavirus and human papillomavirus (HPV).
The hierarchical nature of this modeling technique should prove amenable for use in developing compact mechanisms for other large n-alkanes, and this partially reduced skeletal model can serve as a validated starting model for developing more compact representations.
A more market-driven model by developing more S&T initiatives to match the strategic directions of different enterprises, particularly SOEs, is recommended.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com