A mathematical model describing continuous microbial culture and harvest in a chemostat, incorporating a control strategy and defined by impulsive differential equations, is presented and investigated.
A phenomenological model describing continuous thickening has been previously developed with primary inputs being the material properties, (compressive yield stress and hindered settling function) derived from routine laboratory batch settling and filtration tests.
Models describing continuous PD metrics often represent the concentration effect relationship as a continuous function (e.g., linear, Emax, or sigmoid Emax).
The second component of the model describes the continuous portion of the data with probability 1− πA as truncated log-normal distribution using a sigmoidal Emax function: where Base is the baseline value for free receptor, Emax is maximal drug effect, Cp is drug concentration, EC50 is the concentration of drug at half-maximal response, and γ is the Hill coefficient.
MAUP a fundamental geographical problem endemic to all studies of spatially aggregated data, arising from the need to model or describe continuous spatial phenomena with discrete geographic units.
This approach integrated Bayesian network and Gaussian mixture models to describe continuous microarray gene expression measurements, and three gene networks were predicted.
The so-called flexible matrix model describes rapid and continuous changes of the synaptic architecture driven by the actin cytoskeleton [24].
Since the continuous fermentation proceeds under a steady state (that is, a little change of the initial conditions would not cause a great change of the solutions), the existence of an equilibrium solution and the stability analysis are necessary to evaluate a model describing the continuous fermentation.
In this paper, the model prediction uncertainty is evaluated for a model describing the continuous drying of single pharmaceutical wet granules in a six-segmented fluidized bed drying unit, which is part of the full continuous from-powder-to-tablet manufacturing line (Consigma™, GEA Pharma Systems).
