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In particular, if there are key points in time when data collection practices or underlying data changes occurred, temporal datasets are generated for model derivation purposes based on these key time points.
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Besides the mathematical model derivation for x-Folded TM architecture, we discuss the simulation experiment in x-Folded TM using the same assumptions for the purpose of validation.
Generating reports to document model derivation and simulation results.
Refer to Supplementary Methods (section S2) for model derivation and major assumptions.
The paper discusses the model derivation and implementation.
Universal evolutionary constraints form another basis for mechanistic model derivation.
For model derivation we randomly selected 3 out of 7 hospitals.
(further information and derivations can be found in the "Model Derivation" section of Additional file 1).
Fitting the stratified model (equation 1) is a 1-stage approach to model derivation across studies.
Model derivation and assessment of model performance was performed by using R software version 2.6.0.
Hereafter this dataset is referred to as the model derivation dataset.
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