Sentence examples for model deletion of from inspiring English sources

Consistent with this model, deletion of the last 121 amino acids (aa 546 667) from the C-terminal half of GCP-WD, which does not include serine 418, also abolished Plk1 binding (data not shown).

However, in this model deletion of ATF4 alone had no effect on pathology.

In this yeast model, deletion of BTN1 leads to secretion of the vacuolar protease Cpyp as a consequence of mistrafficking of its receptor, Vps10p (Codlin and Mole, 2009).

In an C. elegans model, deletion of HDAC4 gene increases long-term memory for thermosensation in an CamKII-dependent manner (Wang et al, 2011).

Consistent with this model, deletion of REG1 results in constitutive activation of Snf1 and hyperphosphorylation of its activation loop (McCartney and Schmidt 2001).

In the proposed model, deletion of the N-terminal strap impairs actin bundling, while deletion of the C-terminus enhanced actin bundling.

In animal models, deletion of several of these genes results in low nephron endowment including PAX2, p53, GLI3R, GDNF, FGF 7, FRS2 and Six2 [ 11, 12].

In both of these tumor models, deletion of Akt1 resulted in a dramatic defect in tumor induction, while in contrast, tumorigenesis was accelerated in Akt2-deficient mice.

In both the ALS and AD models, deletion of the prostaglandin E2 receptor significantly slowed disease progression (de Boer et al, 2014; Johansson et al, 2015).

Using mouse models, deletion of APC, or constitutive activation of oncogenic β-catenin in the Lgr5 stem cell compartment of the small intestine identified them as cells-of-origin of intestinal neoplasia [ 11, 12].

Although microglial expression of CX3CR1 has been linked with limiting microglial neurotoxicity in a wide array of neurodegenerative models, deletion of CX3CR1 reduced neuronal loss in amyloid transgenic mice (Cardona et al., 2006; Fuhrmann et al., 2010).