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It also addressed whether the combination of differently expressed miRNA together with clinical parameters in a statistical model could distinguish between endometriosis patients and controls.
We tested if a PLS-DA model could distinguish between uninfected and infected cells for both primary cultured TCM and cell line experimental models in response to CD3/CD28 or PMA/I stimulation.
When shown two photos, one of a gay man and one of a straight man, Kosinski and Wang's model could distinguish between them eighty-one per cent of the time; for women, its accuracy dropped slightly, to seventy-one per cent.
The presence of lignin was modelled using linear discriminant analysis (LDA), where the model could distinguish between high and low lignin content with 88% accuracy.
Furthermore, we tested if the HSL model could distinguish TRR-containing regions from those not containing TRRs.
Areas under the receiver operating characteristic curves (AUROCs) were used to evaluate how well the model could distinguish AKI patients with sepsis from non-AKI patients with sepsis.
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Thus, not only did taking hierarchical population structure into account improve the analysis, but the two models could distinguish between the processes of coevolution and conditional influence.
The researchers also identified 16 Myc targets using their model that could distinguish between advanced and low-grade human liver tumours.
Moreover, a holistic statistical approach was put forward to develop a model which could distinguish 4 categories of drugs with different mechanisms of action.
This metabolite model could differentiate between HIE and controls with an AUC of 0.93 and demonstrated the potential to distinguish between injury severities.
Importantly, the model could not distinguish systematic from opportunistic cervical cancer screening.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com