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Initial experiments show that not only oligophenylenes as model compounds but also the polypropellane can be dendrimerized to a high degree of conversion.
Addition of a strong base such as NaOH significantly enhanced the activity and selectivity for C-O bond hydrogenolysis over undesired hydrogenation reactions, not only in lignin model compounds but also in real lignin conversion.
Other solid bases, such as RbCO3 CsCO3, have also shown promise for β-O-4 cleavage of ether bonds in lignin model compounds, but are able to suppress char formation and increase bio-oil yield [65, 66].
Homogeneous catalysts have been rarely utilised due to their inherent disadvantages in respect of their difficult separation from the reaction mixture, corrosiveness (in the case of soluble acid catalysts), and, hence, are more favoured for selective bond cleavage within model compounds, but have been implemented in oxidative depolymerisation [21, 22].
In this study, we used HIV protease inhibitors as model compounds, but the approach is also applicable to other drugs.
Note that it is not our aim to give a perfect spectroscopic description of pure model compounds, but that we want to illustrate the experimental 2p3d RXES sensitivity to d d excitations and show that RXES theory correlates these well to the ligand field.
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The presence of the catalyst increased the decomposition rate of the model compound but decreased the degradation rate of polystyrene as measured by evolution of low molecular weight products.
There are many potential mechanisms for hBChE resistance to nerve agent model compounds, including but not limited to hydrolysis, rapid reactivation, resistance to aging, or decreased binding affinity.
Single model compounds have been widely used, but they give a quite simplified picture.
On the other hand, bis(heterocycles) have received a great deal of attention, not only as model compounds for main chain polymers but also because many biologically active natural and synthetic products have molecular symmetry [11 22].
Molecular clusters, however, can be considered model compounds, because they only have surface atoms but (in many cases) no bulk atoms.
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