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Such issues render the incorporation of structural mRNA information into a model challenging.
However, a cyclical pattern and large missing records of this variable in our study population made its integration into our spatial model challenging.
The severe international shortage in qualified intensivists makes the wide implementation of this model challenging at present and even unlikely in many non-tertiary-care hospital ICUs in the near future.
Most models addressing this question are dynamic models requiring many input data limiting their adaptations to a few country settings, but also reducing transparency, hence making the evaluation of the model challenging [ 22].
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In her latest riposte, the model challenged those leaving comments on her Instagram page about her body after sharing a picture of her Sports Illustrated magazine shoot.
The model challenges the current paradigm of star formation and may shed light on one of the biggest mysteries of the early cosmos.
Hence the participatory model challenges the justifications, characteristics and conditions of the representative model, introducing the principle of participative strength (and need) of local boards and citizens.
In a baboon model challenged with a lethal dose of E. coli, the monoclonal antibody C6B7 directed against FXIIa improved survival with higher blood pressure.
We then used a rat model challenged with TNBS to examine whether dietary supplementation with punicic acid would prevent intestinal inflammation.
Some differences between the toxicological paradigm and the infectious disease model challenge their integration.
We discuss how this model challenges the view that endosymbiont-induced thelytoky can only occur in haplodiploid species with specific molecular mechanisms of sex determination.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com