Sentence examples for model cell systems from inspiring English sources

Although stress-induced PBs and SGs have been extensively studied in model cell systems, very little is known about whether they are formed and functional in primary cells.

In vitro models are frequently used to study this cancer but little is known about the differences that may exist between these model cell systems and tumour tissue.

In this chapter, we describe the procedure to design and evaluate dual sgRNAs for plant codon-optimized Cas9-mediated genome editing using mesophyll protoplasts as model cell systems in Arabidopsis thaliana and Nicotiana benthamiana.

These studies indicate that the increased urinary excretion of phosphate and uric acid are specific to NHERF-1 null mice and highlight the fact that predictions about the role of adaptor proteins such as the NHERF proteins obtained from studies of model cell systems must be confirmed in whole animals.

Therefore, to understand the exact biological role of dimers and/or higher order forms of receptors it will be necessary to generate GPCRs that are expressed only as monomeric or multimeric receptor forms in model cell systems.

The purpose of this study was to demonstrate proof of principal that p38 MAPK inhibition can block cytotoxic chemotherapy-induced inflammatory cytokine production without inhibiting drug-induced cytotoxicity using murine peritoneal macrophages and Lewis Lung Carcinoma (LLC1) cells as model cell systems.

In the present study, we designed a model cell system to study the mechanisms of stabilin-1-mediated endocytosis.

A quantitative model cell system indicates that intracellular delivery of even restrained levels of iron oxide (Fe2O3) nanoparticles may affect cell function.

A quantifiable model cell system shows that intracellular delivery of even moderate levels of iron oxide (Fe2O3) nanoparticles may adversely affect cell function.

Using measured and estimated parameter values for the model cell system, we estimate that about 90% of the observed kinetic detachment behavior originates from heterogeneity effects, while about 10% is due to probabilistic binding effects.

In this study, we used a murine lung carcinoma CMT.64 cell line as a model cell system to address this question.