Sentence examples for model cell death from inspiring English sources
In our model, cell death was observed in the heart under conditions where the transgenic receptor was unstimulated.
In the BaD model, cell death could be induced both by direct exposure to ionizing radiation and by bystander signals.
In this model, cell death stimuli could induce LmjMCA processing, releasing the catalytic domain, notably ranging from aa 136 to 218, and the C-terminal domain.
That includes stoichiometric coefficients, uptake kinetics, extracellular transport coefficients (e.g. for O2, as in our model), cell death rates, product inhibition kinetics or environmental pH levels.
Furthermore, cell death results from cell autonomous EphB3 signaling since we can model cell death and ephrinB3 reversal in purified adult OL and OPC cultures.
In our chronic ER stress model, cell death induction is PERK/ATF4 dependent and JNK independent, contrarily to the ADRP model in which CDK5 activates JNK signaling that triggers apoptosis.
Here we have discussed the frequently observed phenotypic heterogeneity in the response of human cells to various death-inducing stimuli as well as the sources of this variability and implications for measuring and modeling cell death.
All that is required is a slight chance of undergoing a symmetric division (selection model parameter = 0.0059, selection model with cell death value = 0.011).
In our simulations, a weak proliferative advantage (selection model parameter = 0.0059, selection model with cell death value = 0.011) was sufficient to drive the clonal expansion and account for the mutant clusters seen in the 80-year-old male we studied.
The pro-apoptotic arm of the ER stress response was excluded from this network model in anticipation of being included in a separate network model on cell death related processes.
While the model treats cell death in the usual phenomenological framework of logistic growth, some consideration of the mechanisms at work such as limitations in blood supply would be valuable, including research into the effects of angiotensin.
