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It was discovered through this research that the choice of model caused significantly different results.
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SasF may also contribute to virulence since in a murine arthritis model of infection a sasF allelic replacement mutant of SH1000 caused significantly less weight loss of the animals compared to control cells (Fig. 4A).
Interestingly, Lu et al. reported that bRFE caused significantly higher rate of chondrocyte death than mRFE in a bovine osteoarticular model.
Menstrual headaches caused significantly higher MIDAS grades.
These variations cause significantly different results in sustainable structural design.
So why is the model causing so many problems?
Fly model causes neurological rethink.
In one model, the carcinogen 7,12-dimethyl-benz- [ a]-anthracene caused a significantly increased incidence of mammary tumors in MMTV-DNR mice compared with wild-type controls [ 28**].
However, HapNP-FA caused a significantly higher overexpression of Runx2.
Similarly, knockdown of the maturational Pr in murine cytomegalovirus (MCMV), a model of β herpesvirus infection, causes a significantly reduced viral load.
In recent risk models, it has been suggested that multiple low-risk variants within the same individual may actually cause a significantly elevated risk for the carrier [ 17].
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