These data highlight the need to diagnose drug resistance among all TB cases, and for innovative models of case detection and treatment for MDR-TB, in order to interrupt transmission and control this emerging epidemic.
In 10 scenarios (Table 3) we examine the effect of uncertainty in the model parameters on case detection, NNS, PPV, and resource requirements expressed as the number of CXRs, SSM and XP tests that needs to be done, assuming TB prevalence is 1%.
Through a strategic partnership with the President's Malaria Initiative and the Senegalese National Malaria Control Program, Volunteer Anne Linn will build on Ian's success by rolling out this active case detection model in 20 villages over the next three months.
The global initiative 'Treatment 2.0' calls for expanding the evidence base of optimal HIV service delivery models to maximize HIV case detection and retention in care.
This was a population-based assessment of community-based case detection models that deployed and assessed the performance of trained HSAs and KIs in identifying blind children.
As estimated by the final model, the risk of higher case detection declines by 20% when the proportion of households with running water increases by 0.1 (10%).
We calibrated the sensitivity of this "standard approach" to a value (i.e. 80%) that provided a reasonable estimate of TB case detection rate (model value 70 = Indian national estimate for smear-positive cases) [ 17].
These three countries did not meet the goal for case detection by models 1 or 2. aTB, tuberculosis; +, positive; PDR, patient diagnostic rate; ref, reference number.
Our model accommodates these multiple pathogen and case detection methods.
The case detection rate in model 1 is not a rate but a ratio: it does not reflect the speed at which cases are detected, but the proportion of incident cases detected.
